Opportunity

Simpler Grants.gov #RFA-HG-28-005

NHGRI Limited Competition: AnVIL Program Renewal for Cloud-Based Genomics Platform

Buyer

National Institutes of Health

Posted

June 02, 2026

Respond By

May 25, 2027

Identifier

RFA-HG-28-005

NAICS

541715

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), is announcing a limited competition funding opportunity for the renewal of the Analysis, Visualization, and Informatics Lab-space (AnVIL) program. - Government Buyer: - National Institutes of Health (NIH) - National Human Genome Research Institute (NHGRI) - Program Overview: - Renewal of the AnVIL platform, a secure, cloud-based environment for large-scale genomic data access, sharing, and analysis - Platform currently hosts over 5 petabytes of data from nearly 300,000 research participants - Key Requirements: - Enhance scalability and interoperability within the NIH data ecosystem - Maintain rigorous security standards, including alignment with Research Authentication Service (RAS) and NIH controlled-access data repositories (CADR) - Integrate emerging data types and AI-based computational tools - Support complex analysis workflows - Expand training and outreach for researchers - Products/Services Requested: - Development, enhancement, and operation of the AnVIL platform - No specific OEMs, vendors, or part numbers are named; this is a grant opportunity for eligible organizations - Unique/Notable Requirements: - Emphasis on security, interoperability, and integration of advanced computational tools - Focus on community resource development and researcher support

Description

The National Human Genome Research Institute (NHGRI) is issuing a Notice of Funding Opportunity (NOFO) for a limited competition renewal of the AnVIL program, a secure cloud-based platform for genomic data access and analysis. The program supports scalable, interoperable, and secure genomic research infrastructure, integrating emerging data types and AI-based computational tools. It also includes training and outreach to enhance researcher capabilities in using AnVIL's datasets and analysis tools. The NOFO is expected to be published in 2027 with an application due date in 2027, utilizing the U54 activity code.

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