SBIR / STTR #PA-27-101

NIH SBIR Phase IIB Strategic Breakthrough Award for Follow-on R&D Funding

This opportunity from the National Institutes of Health (NIH), part of the Department of Health and Human Services (HHS), invites small businesses to apply for the SBIR Phase IIB Strategic Breakthrough Award. - Government Buyer: - National Institutes of Health (NIH), Department of Health and Human Services (HHS) - Purpose and Scope: - Provides follow-on R&D funding to previous NIH SBIR or STTR Phase II awardees - Aims to support biomedical technologies with strong commercial potential, especially those facing regulatory, manufacturing, or market barriers - Applicants must secure 100% matching funds from new private capital or new government sources (excluding prior SBIR/STTR awards) - Clinical trials are optional but must be approved by the relevant NIH component - Products/Services Requested: - Research and development services to advance biomedical technologies from Phase II to commercialization - Unique Requirements: - Only previous NIH SBIR/STTR Phase II awardees are eligible - Projects must align with the missions of participating NIH Institutes, Centers, and Offices - Strong emphasis on commercialization and third-party matching funds - No specific OEMs or vendors are named, as this is a grant opportunity for small business concerns (SBCs)

Description

This solicitation supports previous NIH SBIR or STTR Phase II recipients by providing funding to bridge the gap between Phase II and commercialization, known as the "Valley of Death." Applicants must secure 100% third-party matching funds from new private capital or government funding excluding prior SBIR/STTR awards. The award facilitates follow-on R&D with strong commercial potential aligned with NIH missions. Clinical trials are optional but must be accepted by the relevant NIH Institutes or Centers.

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