MTEC #MTEC-26-PROMPT

Prototype Platform for On-Demand Field Manufacturing of Nucleic Acid Primers and Probes

The Defense Threat Reduction Agency (DTRA) is preparing to solicit proposals for a next-generation, field-deployable manufacturing platform for nucleic acid primers and probes. - Government Buyer: - Defense Threat Reduction Agency (DTRA), Department of Defense - Supported by the Medical Technology Enterprise Consortium (MTEC) - Products/Services Requested: - Development, integration, and demonstration of a fully automated, man-portable, ruggedized prototype platform for on-demand manufacturing of clinical-quality nucleic acid primers and probes - System must integrate synthesis, purification, and quality control of oligonucleotides - Must be operable by non-specialist personnel in austere or far-forward environments - Must meet MIL-STD-810 ruggedization standards - Must use field-stable chemistry and enable room-temperature reagent stability (eliminating cold chain logistics) - Must rapidly produce high-purity oligonucleotides and support decentralized diagnostic response to biothreats - OEMs and Vendors: - No specific OEMs or vendors are named; solicitation is open to qualified offerors with relevant capabilities - Unique/Notable Requirements: - Prototype must be man-portable, fully automated, and ruggedized for military use - Must address hazardous synthesis replacement, field-stable chemistry, and operation by non-specialists - MTEC membership is required to submit a proposal - Multiple awards may be made - Period of Performance: - Up to 24 months anticipated for project execution

Description

The Medical Technology Enterprise Consortium (MTEC) is issuing a pre-announcement for a Request for Project Proposals (RPP) to support the Defense Threat Reduction Agency (DTRA). The project aims to develop a fully automated, man-portable, and ruggedized prototype platform for on-demand, expeditionary manufacturing of clinical-quality nucleic acid primers and probes. The system must operate in austere or far-forward environments by non-specialist personnel and integrate synthesis, purification, and quality control of reagents. The goal is to enable rapid, decentralized diagnostic responses to novel biothreats without reliance on traditional laboratory infrastructure or cold chain logistics.

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