Opportunity

Simpler Grants.gov #PAR-27-040

NIH Small Business Transition Grant for Early-Career Entrepreneurs (R41/R42)

Buyer

National Institutes of Health

Posted

May 27, 2026

Identifier

PAR-27-040

NAICS

541715, 541714

The National Institutes of Health (NIH) is preparing a Notice of Funding Opportunity (NOFO) for the Small Business Transition Grant, aimed at supporting early-career scientists in U.S. small businesses as they move into entrepreneurship. - Government Buyer: - National Institutes of Health (NIH) - Eligibility and Key Requirements: - Open exclusively to U.S. small business concerns as defined by the SBA - Designed for first-time Principal Investigators (PIs) transitioning to entrepreneurship - Requires inclusion of a mentor with measurable effort as key personnel - No cost sharing or matching required - Program Details: - Provides entrepreneurial training, mentoring, and career development for the PI - Utilizes the R41/R42 activity code - Covers a broad range of biomedical and health research areas - Products/Services: - No specific products, OEMs, or vendors are mentioned - Focus is on grant funding for research and business development activities - Unique Aspects: - Emphasis on supporting new entrepreneurs in the biomedical and health research sectors - Structured mentorship and career development are mandatory components

Description

The NIH intends to publish a Notice of Funding Opportunity to invite eligible U.S. small business concerns to submit Small Business Technology Transfer Phase I and Fast-Track grant applications for the Small Business Transition Grant. The program supports early-career scientists transitioning to entrepreneurship, including entrepreneurial training, mentoring, and career development of the Principal Investigator. Applications are not being solicited at this time; this notice provides advance information for potential applicants. The opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort.

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