Simpler Grants.gov #RFA-NS-27-015

NIH Funding Opportunity for Scalable Brain Connectivity Mapping Technologies

The National Institutes of Health (NIH), through the National Institute of Neurological Disorders and Stroke, is issuing a Notice of Funding Opportunity (NOFO) for the BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed). - Government Buyer: - National Institutes of Health (NIH) - National Institute of Neurological Disorders and Stroke - Opportunity Focus: - Funding for research projects developing scalable technologies for brainwide mapping of neural connectivity - Areas of interest include tissue processing, imaging, data alignment, segmentation, annotation, error correction, and integration into neuroscience data environments - Project Scope: - Technologies should enable comprehensive mapping of brain wiring diagrams - Projects may use human, non-human primate, mouse, or other species for validation - Applications should complement existing BRAIN CONNECTS awards - Unique Requirements: - Emphasis on innovation and engineering for scalable, integrative solutions - No clinical trials allowed under this opportunity - OEMs and Vendors: - No specific OEMs or commercial vendors are named, as this is a research grant for technology development - Products/Services Requested: - No commercial products, part numbers, or quantities specified; focus is on research and development of new technologies

Description

This funding announcement by the BRAIN Initiative seeks innovative research projects that develop technologies to generate comprehensive atlases of brain connectivity, focusing on human, non-human primate, and mouse models. Projects may address any aspect of brain connectivity and associated data pipelines to enable faster and more cost-effective generation and interpretation of brain-wide wiring diagrams. Funded projects will be integrated into the BRAIN CONNECTS Network to develop capabilities for generating wiring diagrams across multiple scales. The initiative supports transformative research to understand brain circuit function and its contributions to behavior, aiming to advance neural circuit-based approaches for brain disorder treatments.

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