Opportunity

Simpler Grants.gov #DFOP0018449

Safeguards Development for AI-Enabled Chemical and Biological Molecular Models

Buyer

Bureau of Arms Control and Nonproliferation, Office of the Nonproliferation and Disarmament Fund (ACN/NDF)

Posted

May 21, 2026

Respond By

July 21, 2026

Identifier

DFOP0018449

NAICS

541715, 541714, 541713, 813319

The U.S. Department of State's Bureau of Arms Control and Nonproliferation, Office of the Nonproliferation and Disarmament Fund (ACN/NDF), is seeking proposals for cooperative agreements to develop safeguards against the misuse of AI-enabled molecular models in chemical and biological contexts. - Government Buyer: - U.S. Department of State, Bureau of Arms Control and Nonproliferation, Office of the Nonproliferation and Disarmament Fund (ACN/NDF) - Scope of Work: - Research, technical assessment, and development of safeguards, guidelines, and tools to counter proliferation risks from chemical and biological AI models (CBAIMs) - Deliverables may include codes of ethics, software tools, secure platforms, and international workshops - Projects may address all or a targeted subset of nonproliferation objectives - Funding and Structure: - Total available funding: $4,000,000 - Expected number of awards: 2 to 5 - Cooperative agreement structure, up to 24 months period of performance - Eligibility: - U.S. and foreign non-profit/non-governmental organizations, educational institutions, for-profit organizations, U.S. federal government entities, and public international organizations - Notable Requirements: - Emphasis on international engagement and collaboration - Focus on mitigating misuse of AI in weapons of mass destruction (WMD) proliferation - No specific OEMs or commercial products are named; the opportunity is for R&D and implementation of safeguards - Geographic Scope: - Projects may impact a broad range of countries, including Armenia, Australia, Canada, France, Germany, India, Israel, Japan, the United Kingdom, and others

Description

The Department of State's Office of the Nonproliferation and Disarmament Fund (ACN/NDF) announces an open competition for assistance awards to advance efforts in identifying, evaluating, and developing safeguards against misuse risks from the proliferation of chemical and biological Artificial Intelligence models (CBAIMs). Eligible applicants include domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations. The solicitation encourages proposals addressing all or targeted subsets of key objectives related to nonproliferation. The funding instrument is a cooperative agreement with a total available funding of $4,000,000, expecting 2 to 5 awards.

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