SAM #75N98026Q00369

NIH Solicitation for Next Generation Sequencing Services for Bone Marrow Failure Research

The National Institutes of Health (NIH) is seeking small business providers for Next Generation Sequencing (NGS) services to support clinical research on bone marrow failure syndromes. - Government Buyer: - National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, Office of Logistics and Multiple Acquisition Operations - Contracting office located at 6011 Executive Blvd., Suite 503L, Bethesda, MD - Products/Services Requested: - Next Generation Sequencing (NGS) services for detection of genetic mutations in patients with bone marrow failure syndromes, including aplastic anemia - Sequencing panel must cover approximately 300+ genes relevant to hematologic malignancies (e.g., UBA1 for VEXAS syndrome, TERT, GATA2) - Capability to detect point mutations, insertions/deletions, and structural variants - Must process multiple specimen types: fresh cells, FFPE, cfDNA, peripheral blood, bone marrow, plasma - Turnaround time requirement: 10 calendar days or less from sample receipt - Results must be delivered via a secure electronic portal accessible to authorized government personnel - Vendor must provide sample collection kits and FedEx return labels at no cost to NIH - Standardized methodology required for consistency and reproducibility in longitudinal patient data - OEMs and Vendors: - No specific OEMs or commercial vendors are named in the solicitation - Unique/Notable Requirements: - Small business set-aside under NAICS 621511 (Medical Laboratories) - Focus on clinical research for bone marrow failure and hematologic malignancies - Secure, rapid, and standardized genomic data delivery - Place of Performance: - National Heart, Lung, and Blood Institute (NHLBI), Bethesda, MD

Description

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.(ii) The solicitation number is 75N98026Q00369. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold.The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a firm-fixed-price purchase order to the responsible offeror whose proposal represents the best value to the Government.(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, effective March 13, 2026.(iv) (iv) The associated NAICS code is 621511 ¿ Medical Laboratories, and the small business size standard is $41.5 million.This requirement is set aside for small business concerns.

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