SAM #75N98026Q00362

Specialized Computational Analysis Services for CHIP in Genome Sequencing Data

The National Institutes of Health (NIH), Office of the Director, is procuring specialized computational analysis services for genome sequencing data: - Government Buyer: - National Institutes of Health (NIH), Office of the Director, Office of Logistics and Acquisition Operations - Vendor: - Vanderbilt University Medical Center (performing the analysis) - Services Requested: - Specialized computational analysis to identify clonal hematopoiesis of indeterminate potential (CHIP) in longitudinal whole genome sequencing datasets from the Framingham Heart Study - Recalibration of prior datasets, detection of somatic mutations, and CHIP identification using validated analytical pipelines - Collaboration with the NHLBI intramural team on analyses and publications - Services performed at the contractor's facility with remote data access via dbGaP and TOPMed Data Exchange - Unique/Notable Requirements: - Follow-on contract to maintain methodological consistency and reproducibility with prior work - Non-competitive, brand-name justification for continuity - No specific products, OEMs, or part numbers are listed - Period of Performance: - All analyses to be completed within a four-month period - Places of Performance and Delivery: - NIH Office of the Director, Office of Logistics and Acquisition Operations, Bethesda, MD - NHLBI/Population Sciences Branch, Framingham, MA

Description

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.(ii) The solicitation number is 75N98026Q00362 and the solicitation is issued as a Notice of Intent (NOI) of a non-competitive (notice of intent) combined synopsis solicitation to award a contract or purchase order without providing for full or open competition (including brand-name).This acquisition is conducted under the authority of the FAR Part 12.603¿ Streamlined solicitation for commercial products or commercial services, and is not expected to exceed the simplified acquisition threshold, and the authority of 41 U.S.C. 1901 and the statutory authority of FAR 6.302-3(a)(2)(ii).The National Institutes of Health, Office of the Director, Office of Acquisitions, intends to negotiate and award a firm-fixed-price purchase order without providing for full and open competition (Including brand-name) to Vanderbilt University Medical Center1161 21st Ave S, Suite D3300 MCN Nashville, TN 37232-0001 for specialized computational analysis services to identify clonal hematopoiesis of indeterminate potential (CHIP) in longitudinal whole genome sequencing datasets.This requirement is a follow-on effort to previously completed work performed by the same vendor. Continuation with the same source is necessary to maintain methodological consistency across longitudinal datasets, ensure reproducibility of prior analyses, and avoid duplication of cost and schedule delays associated with revalidation of analytical pipelines.

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