SAM #75N98026Q00353

NIH Procurement of Olink Explore HT Assay Kits for Neurodegenerative Disease Research

The National Institutes of Health (NIH), through the Neurodegenerative Diseases Research Section and the OLAO office, is seeking specialized proteomic assay kits and shipping services to support research on neurodegenerative diseases. - Government Buyer: - Department of Health and Human Services (HHS) - National Institutes of Health (NIH) - NIH OLAO office and Neurodegenerative Diseases Research Section - OEM Highlight: - Olink is the specified Original Equipment Manufacturer (OEM) - Products Requested: - 3 units of the Human Olink Explore HT Assay Kit (part number 98100) - Designed for high-resolution, antibody-based proteomic analyses - Enables mapping of protein abundance levels and data relevant to human biological pathways - Shipping and handling for the assay kits (part number 0001-Shipping) - Notable Requirements: - Kits must provide abundance data for thousands of proteins and support mapping to human biological pathways relevant to therapeutics - All items must be delivered in immediately usable and acceptable condition, packaged and marked per government specifications - Delivery required within one month of purchase order receipt - One-year manufacturer's warranty included - Place of Performance and Delivery: - NIH facilities in Bethesda, Maryland

Description

Statement of Need and Purpose: This acquisition is necessary to provide supplies and reagents to the Neurodegenerative Diseases Research Section for neurodegenerative disease research for proteomic analyses. 2. Background Information and Objective: Our project is focused on advancing our understanding of neurodegenerative diseases, particularly parkinsonism syndromes, through detailed analyses of human samples using state-of-the-art Olink Explore assays. By leveraging these assays, we will perform highresolution proteomics to map protein expression profiles across samples obtained from patients, thereby illuminating the complex molecular landscape of neurodegeneration. 3. Generic Name of Product: Human Olink Explore HT Assay Kit 4. Purchase Description: Item Description Cat no Quantity Total Cost Olink Explore HT Reagent Kit 98100 3 @ $68,800 ea $206,400.00 Shipping and Handling 0001-Shipping 1 @ $461.31 $461.31 Order Total $206,861.31 5. Salient characteristics. All deliverables required under this contract shall be packaged, marked, and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and the Contractor's name. The Contractor shall guarantee that all required materials shall be delivered in an immediately usable and acceptable condition. The vendor must be able to provide these specifications: • Must use an antibody-based approach to map protein abundance levels within samples. • Must provide the abundance levels for thousands of proteins within the samples. • Must be able to provide data that can be mapped to human biological pathways and processes that are potentially targetable by therapeutics. 6. Quantity: Item Description Cat no Quantity Total Cost Olink Explore HT Reagent Kit 98100 3 @ $68,800 ea $206,400.00 Shipping and Handling 0001-Shipping 1 @ $461.31 $461.31 Order Total $206,861.31

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