Opportunity
Simpler Grants.gov #RFA-OD-27-003
NIH INCLUDE Project: Exploratory/Developmental Research Awards for Down Syndrome
Buyer
National Institutes of Health
Posted
February 12, 2026
Respond By
February 19, 2026
Identifier
RFA-OD-27-003
NAICS
541714, 541715
The National Institutes of Health (NIH) is inviting applications for the INCLUDE Project, which funds exploratory and developmental research on Down syndrome. - Government Buyer: - National Institutes of Health (NIH) is the sole government agency involved - Products/Services Requested: - Research services focused on Down syndrome, including: - Feasibility studies for novel investigations - Development of new experimental systems - Innovative uses of existing methodologies - Projects with significant risk aiming for breakthroughs or new techniques, agents, methodologies, models, or applications in biomedical, behavioral, or clinical research - OEMs and Vendors: - No specific Original Equipment Manufacturers (OEMs) or vendors are named; the opportunity is for research services only - Unique/Notable Requirements: - Projects must address critical needs in Down syndrome research - High-risk, high-reward research is encouraged - No cost sharing or matching required - Open to a wide range of organizations, including educational, governmental, nonprofit, business, and foreign institutions - Funding Details: - Total program funding: $1,000,000 - Individual awards: $50,000 to $200,000 - Up to 5 awards expected
Description
The NIH INCLUDE Project invites researchers to submit applications for exploratory and developmental research projects addressing critical needs in Down syndrome research. Projects may assess novel areas of investigation or new experimental systems with potential to enhance health-related research. Studies may involve risk but aim to lead to breakthroughs or development of novel techniques, methodologies, or applications impacting biomedical, behavioral, or clinical research. The funding supports projects that align with the INCLUDE Project objectives to improve health and quality of life for individuals with Down syndrome.