SBIR / STTR #CBD254-011

DoD SBIR Solicitation for Expeditionary Biologics-on-Demand and Advanced Chemical/Biological Defense Technologies

This Department of Defense SBIR opportunity, managed by the Defense Threat Reduction Agency (DTRA) and the Joint Science and Technology Office for Chemical and Biological Defense (JSTO CBD), seeks innovative research and development proposals for expeditionary biologics-on-demand and advanced chemical/biological defense technologies. - Government Buyer: - Department of Defense (DoD) - Defense Threat Reduction Agency (DTRA) - Joint Science and Technology Office for Chemical and Biological Defense (JSTO CBD) - Products/Services Requested: - Research and development services for: - PFAS-free regenerable respirator particulate filtration systems - Novel SERS sampling tickets for chemical/biological threat detection - Integrated deployable microsensors for chemical detection - Far forward manufacturing of CBRN sensors - Tactical CB visualization tools (including augmented reality) - Shelf-stable nucleic acid synthesis reagents for field diagnostics - Portable biologics-on-demand protein production systems (BOND) - Microphysiological systems for vaccine evaluation (MAGPIE) - No specific part numbers or quantities; focus is on prototype development and demonstration - OEMs and Vendors: - No specific OEMs or commercial vendors are named; opportunity is open to small businesses capable of R&D and commercialization - Unique/Notable Requirements: - Solutions must be suitable for military operational environments, including expeditionary and far-forward settings - Emphasis on ruggedization, automation, machine learning, and shelf-stability for field use - Compliance with SBIR and STTR Extension Act of 2022 - Disclosure of foreign nationals involved in the project - Adherence to detailed technical requirements per topic - Period of Performance: - Phase I: Up to 6 months (some topics 4 months) - Direct to Phase II: Up to 12 months base + 12 months option (total up to 24 months) - Phase II: Generally 12-24 months - All awards subject to funding availability - Place of Performance: - Defense Threat Reduction Agency (DTRA), federal facility

Description

This solicitation is an open topic under the DoD SBIR 2025.4 program for Expeditionary Biologics-on-Demand (BOND). It invites small business concerns capable of conducting research and development and commercializing results in defense-related areas. The program focuses on chemical and biological defense technologies including detection, protection, hazard mitigation, medical countermeasures, diagnostics, and information systems. Proposals are accepted for Phase 1, Phase 2, and Phase 2S (SPII) with a response deadline of July 31, 2023.

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