Opportunity

SBIR / STTR #CBD254-006

DoD SBIR Solicitation: Novel SERS Sampling Tickets and Advanced Chemical/Biological Defense Technologies

Buyer

Department of Defense, Chemical and Biological Defense Program

Posted

September 03, 2025

Respond By

September 24, 2025

Identifier

CBD254-006

NAICS

541715, 541713, 541714

The Department of Defense is seeking innovative small business solutions to advance chemical and biological defense technologies, with a focus on novel sampling tickets for Surface Enhanced Raman Spectroscopy (SERS) to detect chemical and biological threat materials. - Government Buyer: - Department of Defense (DoD) - Defense Threat Reduction Agency (DTRA) - Joint Science and Technology Office for Chemical and Biological Defense (JSTO CBD) - OEMs and Vendors: - No specific OEMs or vendors are named; opportunity is open to all qualified small businesses with relevant R&D capabilities - Products/Services Requested: - Research and development of flexible, semi-porous sampling coupons embedded with plasmonic nanoparticles for SERS - Prototypes must demonstrate enhanced sensitivity and selectivity for trace detection of nerve agents, toxins, and hazardous substances on various surfaces - Deliverables include at least 50 prototype substrates for independent analysis and performance demonstration with chemical surrogates - Additional related R&D topics include: - PFAS-free regenerable respirator filters - Integrated deployable microsensors for chemical detection - On-demand manufacturing of CBRN sensors - Tactical CB visualization tools (e.g., augmented reality) - Shelf-stable nucleic acid synthesis reagents for field diagnostics - Portable biologics-on-demand protein production systems - Microphysiological systems for vaccine evaluation - Unique or Notable Requirements: - Emphasis on innovative, flexible, and field-deployable SERS sampling technologies - Proposals must address substrate selection, design, fabrication, and patterning for SERS enhancement - Performance demonstrations must use relevant chemical surrogates and statistical analysis of detection limits - Transition plans for fielding across military services, Special Operations, and National Guard Bureau, with potential dual-use in homeland security and commercial sectors - Set aside for small businesses under the SBIR program - Period of Performance: - Phase I: Up to 6 months (some topics as short as 4 months) - Direct to Phase II: Up to 12 months base + 12-month option (total up to 24 months) - Phase II: Generally 12-24 months - Maximum funding for Phase I around $209,575; Phase II up to approximately $1.4 million

Description

This solicitation is part of the Department of Defense Small Business Innovation Research (SBIR) program, specifically under the Chemical and Biological Defense Program (CBDP). It seeks innovative research and development proposals for novel sampling tickets designed for Surface Enhanced Raman Spectroscopy (SERS) to detect chemical and biological threat materials. The program aims to improve defensive capabilities against chemical and biological weapons, supporting the U.S. military's readiness and effectiveness. Proposals must comply with the terms of the announcement and are subject to evaluation for scientific and technical quality.

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