Simpler Grants.gov #HT942526TSCRPCTRA

Army and DHA Grant for Clinical Translational Research on Tuberous Sclerosis Complex

This opportunity invites applications for clinical translational research on tuberous sclerosis complex (TSC) through the Department of the Army and the Defense Health Agency (DHA): - Government Buyer: - Department of the Army, US Army Medical Research Acquisition Activity (USAMRAA) - Defense Health Agency (DHA), Congressionally Directed Medical Research Programs (CDMRP) - Funding Details: - Approximately $3.5 million available for about two awards - Single Principal Investigator (PI) applications capped at $1.6M; partnering PI applications capped at $1.9M - Maximum period of performance is 3 years - Products/Services Requested: - Clinical translational research projects advancing preclinical or clinical findings toward clinical application for TSC - Focus areas include neuropsychiatric disorders, tumor prevention, epilepsy, diagnostic technologies, and maternal-fetal health - Eligible research may include pilot clinical trials, biomarker development, and clinical care improvement - Unique/Notable Requirements: - No specific OEMs or vendors are named; this is a research grant - Multiple PIs allowed, with distinct requirements for partnering applications - Two-step application process; withdrawal possible if any associated application is rejected - Broad eligibility: extramural/intramural, foreign/domestic, for-profit/nonprofit, public/private organizations - Mandatory registrations in SAM.gov, eBRAP.org, and Grants.gov

Description

The fiscal year 2026 (FY26) Tuberous Sclerosis Complex Research Program (TSCRP) Clinical Translational Research Award (CTRA) supports studies that will move promising, well-founded preclinical and/or clinical research findings closer to clinical application, including diagnosis, prognosis or treatment of tuberous sclerosis complex (TSC). This funding mechanism allows for multiple Principal Investigators (PIs), with only the initiating PI submitting a pre-application, but all PIs required to submit full applications. The partnering PI(s) application is an abbreviated package specific to their distinct portion of the research project. The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $3.5 million to fund approximately two Clinical Translational Research Award applications with total cost caps of $1.60M for single PI applications and $1.90M for partnering PI applications. The maximum period of performance is 3 years.

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