Simpler Grants.gov #PAR-27-075

NIH Grant Opportunity: Research on Skin Injury Mechanisms from Toxic Chemicals

This opportunity is a forecasted research grant from the National Institutes of Health (NIH), targeting skin injury mechanisms caused by toxic chemicals. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - National Institute of Allergy and Infectious Diseases (NIAID) - Products/Services Requested: - Scientific research services focused on the molecular and cellular pathology of skin injury from at least two toxic chemicals from different toxidromes - Chemicals of interest include vesicants such as sulfur mustard, Lewisite, nitrogen mustard, phosgene oxime, arsenicals, and other toxic agents - Goal is to identify shared therapeutic targets and develop broad-spectrum medical countermeasures - Unique/Notable Requirements: - Applicants must study at least two chemicals from different toxidromes - Research must address high-consequence public health threats as identified by the U.S. Department of Homeland Security - No specific OEMs or vendors are named; this is a grant for research services, not product procurement - Place of Performance: - National Institutes of Health (NIH)

Description

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the National Institute of Allergy and Infectious Diseases (NIAID) are soliciting applications to study the pathological mechanisms of skin injury caused by toxic chemicals identified as high-consequence public health threats. The research will focus on understanding common mechanisms of skin injuries caused by vesicants such as sulfur mustard, Lewisite, nitrogen mustard, phosgene oxime, arsenicals, and other toxic chemicals. Applications should investigate the molecular and cellular pathology of at least two chemicals from different toxidromes. The goal is to discover potential shared therapeutic targets and develop broad-spectrum medical countermeasures for chemical injuries. This initiative is part of a NIH-wide effort under the Chemical Countermeasure Research Program (CCRP).

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