Simpler Grants.gov #PAR-27-081

NIH Grant Forecast: Discovery of in vivo Chemical Probes for Brain Targets

This opportunity is a forthcoming research grant from the National Institutes of Health (NIH), led by the National Institute on Aging (NIA), to support the discovery of in vivo chemical probes for novel brain targets. - Government Buyer: - National Institutes of Health (NIH) - National Institute on Aging (NIA) - In collaboration with: National Eye Institute (NEI), National Institute on Drug Abuse (NIDA), National Institute of Mental Health (NIMH) - Products/Services Requested: - Research and development of novel small molecule chemical probes for brain targets - Validation of new biological targets relevant to brain disease mechanisms - Applicants must have validated starting compounds and bioassays for testing new analog compounds - Unique/Notable Requirements: - Focus on in vivo chemical probe discovery and optimization - No specific products, part numbers, or OEMs are mentioned - Open to a wide range of eligible applicants (educational institutions, government, nonprofits, businesses, certain foreign organizations) - No cost sharing or matching required - This is a forecast notice; applications are not yet being solicited

Description

The National Institute on Aging (NIA) plans to publish a Notice of Funding Opportunity (NOFO) to support investigators interested in discovering in vivo chemical probes for novel brain targets. Collaborating institutes include the National Eye Institute (NEI), the National Institute on Drug Abuse (NIDA), and the National Institute of Mental Health (NIMH). Applicants are expected to have starting compounds for chemical optimization and bioassays for testing new analog compounds. The research aims to discover and develop novel small molecules and validate novel biological targets relevant to brain disease mechanisms. Applications are not currently being solicited; this notice allows potential applicants time to develop collaborations and projects.

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