Opportunity

Simpler Grants.gov #PA-25-307

NIH Exploratory/Developmental Research Project Grant (Parent R21) for Basic Experimental Studies with Humans

Buyer

National Institutes of Health

Posted

December 18, 2024

Respond By

May 24, 2026

Identifier

PA-25-307

NAICS

541715

The National Institutes of Health (NIH) is seeking applications for the Exploratory/Developmental Research Project Grant (Parent R21) focused on basic experimental studies with humans. - Opportunity supports early-stage, high-risk research projects in biomedical, behavioral, or clinical science - Projects must involve prospective assignment of human participants to conditions and assessment of biomedical or behavioral outcomes - Research should aim to understand fundamental phenomena, not specific products or applications - Projects must align with the scientific missions of participating NIH Institutes and Centers - No specific OEMs, vendors, or commercial products are requested - Eligible applicants include higher education institutions, nonprofits, businesses, tribal governments, and other organizations

Description

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, which are prospective basic science studies involving human participants that meet the NIH definition of a clinical trial and basic research. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers based on their scientific missions.

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