Opportunity

Simpler Grants.gov #PAR-28-009

NIH Grant for Research on Non-Addictive Natural Products for Chronic Pain

Buyer

National Institutes of Health

Posted

April 22, 2026

Respond By

May 25, 2027

Identifier

PAR-28-009

NAICS

541715

The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), is seeking proposals for collaborative interdisciplinary research on non-addictive natural products for chronic pain management. - Government Buyer: - National Institutes of Health (NIH) - National Center for Complementary and Integrative Health (NCCIH) - Scope of Research: - Focus on non-addictive natural products, including botanicals, dietary supplements, and other naturally derived compounds - Emphasis on holistic, system-oriented approaches to pain management - Research should address effects across multiple organ systems - Projects should optimize dosing and intervention timing for maximum therapeutic benefit - Unique Requirements: - Interdisciplinary collaboration is encouraged - Research must align with the NIH HEAL Initiative to promote safe, non-addictive pain relief strategies - No specific OEMs or vendors are named, as this is a grant opportunity for research, not a product procurement - Eligible applicants include government, business, educational, nonprofit, and other organizations

Description

The National Center for Complementary and Integrative Health (NCCIH) is seeking collaborative interdisciplinary research to advance foundational understanding of non-addictive natural products for chronic pain management through a holistic, system-oriented approach. The initiative supports the NIH HEAL Initiative by promoting safe, non-addictive, and prevention-oriented strategies for pain relief. Research should examine how natural products influence pain through coordinated biological pathways across multiple organ systems and explore dose optimization and intervention timing. The program emphasizes rigorous mechanistic studies to inform future translational research and guide development of evidence-based pain management strategies.

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