Opportunity

Simpler Grants.gov #DE-FOA-0003612

DOE Genesis Mission: AI-Driven Science and Energy Innovation Solicitation

Buyer

DOE Office of Science

Posted

March 17, 2026

Respond By

December 17, 2026

Identifier

DE-FOA-0003612

NAICS

541715

This opportunity from the Department of Energy (DOE) seeks to accelerate AI-driven breakthroughs in science, energy, and national security through the Genesis Mission: - Government Buyer: - United States Department of Energy (DOE), including the Office of Science and National Nuclear Security Administration (NNSA) Laboratory complex - Products/Services Requested: - Research and development services for novel artificial intelligence (AI) models and frameworks - Execution of project agreements for public-private partnerships - Data curation and preprocessing for AI/ML models - Creation and delivery of AI models with unlimited government rights - Integration of AI solutions with DOE/NNSA resources, National Laboratories, industry, and academia - Focus Areas: - Advanced manufacturing, biotechnology, critical minerals, nuclear fission and fusion, quantum information science, semiconductors, microelectronics, discovery science, and energy - Unique/Notable Requirements: - Cost sharing is required - Foreign entity participation is generally prohibited - Compliance with DOE/NNSA laboratory regulations and intellectual property clauses - Work must be performed primarily in the U.S. - Milestone-based payments and deliverables, with unlimited rights to data and AI models for the government - Potential integration with the American Science Cloud - No specific OEMs or commercial vendors are named; the solicitation is open to interdisciplinary teams from industry, academia, and national labs.

Description

The Department of Energy (DOE) Office of Science and several of its offices announce interest in receiving applications from interdisciplinary teams to address the Genesis Mission National Science and Technology Challenges. The goal is to accelerate scientific discovery and R&D workflows using novel AI models and frameworks to advance energy, environmental, and nuclear challenges. Teams are encouraged to leverage DOE/NNSA resources, National Laboratories, industry, and academia. Successful AI models and workflows may be integrated into the American Science Cloud.

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