Simpler Grants.gov #RFA-AI-28-001

NIH Forecast: HIV/AIDS Clinical Trials Network Leadership and Operations Centers

The National Institutes of Health (NIH), through the National Institute of Allergy and Infectious Diseases (NIAID), is forecasting a funding opportunity to establish four HIV/AIDS Clinical Trials Networks (CTNs). - Government Buyer: - National Institutes of Health (NIH) - National Institute of Allergy and Infectious Diseases (NIAID) - Opportunity Overview: - Funding for four Clinical Trials Networks, each with a Leadership and Operations Center (LOC) - Each CTN will also include a Statistical and Data Management Center and a Laboratory Center - Scope of Services: - Scientific leadership and research prioritization for HIV/AIDS studies - Conducting clinical trials in areas such as: - HIV therapeutics and cure - Prevention and treatment of HIV-associated comorbidities - Maternal, adolescent, and pediatric HIV prevention and treatment - Biomedical HIV prevention strategies - Immune-based prevention for HIV and related diseases - Implementation research to improve uptake of evidence-based HIV prevention and treatment - Notable Requirements: - Applicants must propose comprehensive research agendas for their CTN - Emphasis on leadership, coordination, and operational support for multi-site clinical research - No specific OEMs, vendors, or commercial products are mentioned, as this is a research grant opportunity, not a product procurement.

Description

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to support four Clinical Trials Networks (CTNs), each with a Leadership and Operations Center (LOC), Statistical and Data Management Center, and Laboratory Center, to advance HIV prevention, treatment, and implementation research aimed at ending the HIV epidemic. This NOFO will solicit applications for four LOCs to provide scientific leadership, research prioritization, and conduct studies in a CTN. LOCs will develop research agendas in areas such as HIV therapeutics/cure, prevention/treatment for HIV-associated comorbidities, maternal/adolescent/pediatric HIV prevention/treatment, biomedical HIV prevention strategies, and immune-based prevention for HIV and related diseases. The CTNs will conduct HIV implementation research to improve the uptake of evidence-based prevention and treatment strategies across the lifespan. High-impact studies will produce significant benefits for Americans with or at risk of HIV.

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