Opportunity

Simpler Grants.gov #RFA-AR-26-006

NIH Forecast: RE-JOIN 2.0 Research Funding Opportunity for Joint Health and Pain Reduction

Buyer

National Institutes of Health

Posted

January 22, 2026

Respond By

December 01, 2026

Identifier

RFA-AR-26-006

NAICS

541715

The National Institutes of Health (NIH), through the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other NIH partners, is announcing an upcoming funding opportunity for the Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0 initiative. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - Purpose and Scope: - Forecasted Notice of Funding Opportunity (NOFO) for research grants under the RE-JOIN 2.0 initiative - Part of the NIH Helping to End Addiction Long Term (HEAL) initiative - Focus areas include: - Mapping and refining the innervation of joint tissues by sensory neurons involved in pain - Enhancing clinical pain phenotyping - Expanding preclinical modeling of joint pain - Testing novel joint-targeted therapeutic candidates - Improving data integration and joint tissue atlases - Products/Services Requested: - No specific products, part numbers, or OEMs are mentioned - The opportunity is for cooperative agreement research grants, not product procurement - Unique/Notable Requirements: - Multidisciplinary collaborations are encouraged - Open to a wide range of eligible organizations, including educational, nonprofit, governmental, business, and foreign institutions - Advance notice provided to allow for project and team development - No applications are being accepted at this time; this is a forecasted opportunity

Description

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), in conjunction with other NIH Institutes and Centers, plans to publish a Notice of Funding Opportunity (NOFO) to advance the Restoring Joint Health and Function to Reduce Pain (RE-JOIN) Consortium. The NOFO aims to refine and map the innervation of joint tissues by sensory neurons mediating pain and expand efforts including clinical pain phenotyping, preclinical modeling, testing novel joint-targeted candidates, and improving data integration through joint atlases. Applications are not currently being solicited; this notice allows potential applicants time to prepare multidisciplinary collaborations and projects. Expertise in neurobiology, pain science, data science, orthopedics, and rheumatic disease is encouraged for future applications.

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