Opportunity

Simpler Grants.gov #RFA-RM-26-001

NIH Director’s Pioneer Award Program Research Grant Opportunity

Posted

December 11, 2025

Respond By

September 09, 2026

Identifier

RFA-RM-26-001

NAICS

541715

This opportunity invites applications for the NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional), supporting groundbreaking biomedical research: - Government Buyer: - National Institutes of Health (NIH), a federal agency - Program Details: - Part of the High-Risk, High-Reward Research (HRHR) Program under the NIH Common Fund - Seeks exceptionally creative scientists with bold, innovative research proposals - Aims for projects with major impact in areas relevant to the NIH mission - Eligibility: - Open to higher education institutions, government entities, businesses, nonprofits, tribal organizations, and foreign institutions - Funding: - Estimated total program funding: $8,100,000 - Expected individual award: $700,000 - Approximately eight awards anticipated - Products/Services: - No specific products, OEMs, or vendors requested; this is a research grant, not a product or service procurement - Notable Requirements: - Supports both clinical trial and non-clinical trial research - Emphasizes high-risk, high-reward projects and individual investigator creativity

Description

The NIH Director’s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. Applications in any area within the biomedical sciences are welcome. The award is part of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

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