Opportunity

Simpler Grants.gov #RFA-DK-27-108

NIH Solicits Research Applications for CARE-T1D Consortium U01 to Advance Cardiovascular Disease Understanding in Type 1 Diabetes

Buyer

National Institutes of Health

Posted

September 18, 2025

Identifier

RFA-DK-27-108

NAICS

541715

The National Institutes of Health (NIH), through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Heart, Lung, and Blood Institute, is soliciting research applications for the CARE-T1D Consortium U01 initiative. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) - National Heart, Lung, and Blood Institute - Purpose: - Fund discovery and mechanistic research to advance understanding of cardiovascular disease in type 1 diabetes (T1D) - Emphasis on multi-omics and molecular approaches - Encourage collaborative teams with expertise in T2D, atherosclerosis, inflammation, and advanced omics techniques - Consortium Details: - CARE-T1D Consortium formed with six research teams focused on cardiac disease pathogenesis in T1D - New funding opportunity to expand research scope and participation - Funding Details: - Estimated total funding: $4,500,000 - Up to eight awards expected - No cost sharing or matching required - Funding instrument: Cooperative agreement (U01) - Products/Services Requested: - Research services in cardiovascular disease and type 1 diabetes using advanced scientific methods - Unique Requirements: - Focus on multi-omics, molecular, and collaborative research - Open to investigators with relevant expertise; encourages cross-disciplinary teams - No specific OEMs or commercial vendors are named, as this is a research grant opportunity.

Description

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), in collaboration with the National Heart, Lung, and Blood Institute, is soliciting applications for research to advance understanding of cardiovascular disease in type 1 diabetes through continuation of the CARE-T1D consortium. The consortium, formed in 2024, conducts hypothesis-driven research on cardiac disease pathogenesis in T1D using multi-omics and molecular approaches. This funding opportunity uses the U01 mechanism for investigative teams and encourages collaborative investigations involving expertise in T2D, atherosclerosis, inflammation, and omics techniques.

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