Simpler Grants.gov #RFA-AI-27-009

NIH Solicitation: Centers for Structural Biology of HIV and Infectious Diseases

This opportunity from the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH) seeks to establish Centers for Structural Biology of HIV and other Infectious Diseases. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Allergy and Infectious Diseases (NIAID) - Purpose: - Support multidisciplinary research teams to determine 3D structures of molecules and complexes involved in priority infectious diseases, including HIV - Advance high-resolution structural analysis, computational molecular dynamics, and atomic-level visualization - Enable structure-guided design of molecules for new medicines and diagnostics - Products/Services Requested: - Structural biology research services (no specific products or part numbers) - Focus on advanced research technologies and methodologies - Unique Requirements: - Centers must maximize use of shared resources and foster broad collaborations - Emphasis on mentoring future researchers and supporting diverse teams - Open to a wide range of eligible organizations, including nonprofits, educational institutions, government entities, businesses, and foreign institutions - No specific OEMs or vendors are named, as this is a research grant solicitation

Description

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to support multidisciplinary groups of scientists to determine the 3-dimensional structures of molecules and molecular complexes involved in priority infectious diseases. The centers will focus on exploring biomolecular complexes that can be targeted to develop new medicines and tests to prevent or treat infections and improve human health. Research will include high-resolution 3D structural analyses, computational molecular dynamics, functional and mechanistic characterization, atomic-level visualization, and advanced structure-guided design of molecules. The centers will also maximize use of common resources, establish broad collaborations, and mentor future structural biology researchers.

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