Simpler Grants.gov #PAR-25-049

NIH SIREN Neurologic Clinical Trials Funding for Multi-Center Research Services

This opportunity from the National Institutes of Health (NIH) seeks applications for multi-center clinical trials in neurological emergencies under the SIREN (Strategies to Innovate EmeRgENcy Care Clinical Trials Network) program. - Government Buyer: - National Institutes of Health (NIH) - SIREN Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC) provide support - Products/Services Requested: - Multi-center clinical trial services focused on neurological emergencies - Implementation, statistical, and data management support provided by SIREN CCC and DCC - Collaboration with SIREN network hubs, affiliated clinical sites, and potentially other US/international consortia - Eligible Applicants: - Higher education institutions, nonprofits, government entities, small businesses, and other organizations - Unique/Notable Requirements: - No specific OEMs or vendors are named - No physical products are being procured; focus is on clinical research services and collaboration within the SIREN network - Emphasis on large-scale, multi-site trial capability and integration with SIREN infrastructure

Description

This announcement encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network, with support from the NIH SIREN Clinical Coordinating Center and Data Coordinating Center. The NIH SIREN hubs and affiliated clinical sites will implement the clinical protocols on-site. The network is also positioned to collaborate with other US and international consortia for larger trials. Multi-center clinical trials in stroke treatment supported by NINDS will be conducted in the NIH StrokeNet, not within SIREN.

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