Simpler Grants.gov #PAR-26-152

NCI PAIRS Program Solicits Research Projects on Radiation-Synthetic Combination Strategies for Cancer Therapy

The National Cancer Institute (NCI) is inviting research proposals under the Precision Approaches in Radiation Synthetic Combinations (PAIRS) program to advance cancer therapy. - Government Buyer: - National Institutes of Health (NIH), National Cancer Institute (NCI) - Products/Services Requested: - Research projects focused on identifying and exploiting synthetic vulnerabilities in tumors when paired with radiation therapy - Development of innovative drug-radiation combination strategies for precision medicine in cancer treatment - Project durations: exploratory/developmental (up to 2 years) or research (4 to 5 years) - OEMs and Vendors: - No specific OEMs or vendors are named, as this is a research grant opportunity - Unique or Notable Requirements: - Emphasis on scientific rigor, reproducibility, and alignment with NIH cancer research priorities - Open to a wide range of applicants, including for-profit, nonprofit, educational, governmental, and tribal organizations - Projects must focus on context-dependent effects of radiation therapy and actionable synthetic vulnerabilities - Place of Performance: - National Institutes of Health (NIH)

Description

The National Cancer Institute (NCI) solicits research projects investigating actionable synthetic vulnerabilities paired with tumor responses to radiation therapy. The PAIRS program aims to develop radiation-synthetic combination strategies to enhance precision medicine for anticancer treatments. The program supports innovative cancer therapy strategies exploiting context-dependent effects of radiation therapy using drug-radiation combinations. Applicants may submit exploratory/developmental projects up to 2 years or research projects lasting 4 to 5 years.

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