Simpler Grants.gov #RFA-DK-27-121

NIH Seeks Clinical Centers for Youth Anti-Obesity Medication Research Consortium

The National Institutes of Health (NIH) is seeking clinical centers to join a consortium focused on optimizing anti-obesity medication (AOM) strategies for children and adolescents. - Government Buyer: - National Institutes of Health (NIH) - Products/Services Requested: - Clinical research participation as a consortium member - Activities include protocol development, use of common data elements, centralized laboratory procedures, and collaborative data analysis - Focus on testing AOM initiation, dosage, frequency, adjunct lifestyle therapies, and predictors of treatment response - Unique/Notable Requirements: - Consortium model with shared protocol and data standards - Open to a wide range of eligible applicants (government, academia, nonprofits, businesses) - No specific OEMs or vendors required, as this is a research grant opportunity - OEMs: - No OEMs or product manufacturers are specified, as this is not a product procurement

Description

This Notice of Funding Opportunity invites applications from clinical centers to participate in a consortium to test anti-obesity medication treatment strategies for youth with obesity. The goal is to maximize benefits and minimize risks of AOM use while supporting healthy growth, nutritional status, mental health, and quality of life. Priority areas include determining optimal developmental stage for AOM initiation, weight loss parameters, medication class and dosage, and adjunct lifestyle therapies. The consortium will collaborate on protocol development, data collection, and analysis for independent or multicenter trials.

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