Simpler Grants.gov #PAR-26-124

NIH HEAL Initiative Whole Joint Health Program Research Services Solicitation

This opportunity from the National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), seeks research services for the HEAL Initiative Whole Joint Health Program. - Government Buyer: - National Institutes of Health (NIH) - National Center for Complementary and Integrative Health (NCCIH) - Scope: - Phased mechanistic clinical research program focused on joint pain - Emphasis on multi-tissue mechanisms and non-pharmacological or multimodal interventions - Supports the NIH Helping to End Addiction Long-term (HEAL) Initiative - Program Structure: - Phase 1: Identify and validate multi-tissue mechanisms underlying joint pain - Phase 2: Test interventions such as physical therapy, mind-body approaches, biomechanical strategies, or integrated multimodal treatments - Eligibility: - Open to educational, nonprofit, government, business, tribal organizations, and foreign components - Products/Services Requested: - No specific OEMs or vendors mentioned - No products requested; research services only - Services include imaging, biomarker profiling, neuromuscular assessment, behavioral/environmental factors, and multimodal approaches - Unique Requirements: - Focus on safe, non-addictive, prevention-oriented approaches to chronic pain - Maximum project length of five years

Description

The National Center for Complementary and Integrative Health (NCCIH) plans to support a phased mechanistic clinical research program focusing on understudied biological mechanisms that drive joint pain. The program aims to identify and validate multi-tissue mechanisms underlying joint pain and test non-pharmacological or multimodal interventions targeting these mechanisms. The initiative supports the NIH Helping to End Addiction Long-term (HEAL) Initiative and seeks to advance safe, non-addictive, and prevention-oriented approaches to chronic pain. Projects are divided into two phases: Phase 1 identifies mechanisms, and Phase 2 tests interventions. The total project length cannot exceed 5 years.

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