Opportunity

Simpler Grants.gov #FOR-DA-27-005

NIH Grant for Research on Non-Invasive Brain Stimulation for Substance Use Disorders

Buyer

National Institutes of Health

Posted

September 16, 2025

Respond By

June 05, 2026

Identifier

FOR-DA-27-005

NAICS

541715

The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), is announcing a funding opportunity for research on non-invasive brain stimulation (NIBS) to treat substance use disorders (SUDs). - Government Buyer: - National Institutes of Health (NIH) - National Institute on Drug Abuse (NIDA) - Products/Services Requested: - Basic research services focused on NIBS techniques for SUDs - Research to investigate molecular, cellular, and circuit-level changes from NIBS - Studies to identify mechanisms, therapeutic pathways, and novel clinical targets - Techniques include: - Transcranial Magnetic Stimulation (TMS) - Transcranial Direct Current Stimulation (tDCS) - Transcranial Focused Ultrasound (tFUS) - Unique/Notable Requirements: - Research may use animal and/or human models - Emphasis on understanding neurobiological, cognitive, and behavioral responses to NIBS - No specific OEMs or vendors are named; this is a grant for research, not a product procurement - Estimated total funding is $3,000,000 with approximately four awards - Eligible applicants include government, nonprofits, businesses, and educational institutions - No cost sharing or matching required

Description

The National Institute on Drug Abuse (NIDA) intends to publish a Notice of Funding Opportunity (NOFO) to encourage basic research on Non-Invasive Brain Stimulation (NIBS) using animal and human models. The research aims to elucidate molecular, cellular, and circuit level changes induced by NIBS protocols, identify molecular mechanisms and pathways for therapeutic effects in substance use disorders (SUDs), discover novel clinical targets for NIBS, and investigate neurobiological, cognitive, and behavioral responses to NIBS relevant to SUDs. Applications are not being solicited at this time; the notice is to allow potential applicants time to develop collaborations and projects. Investigators with expertise in neuromodulation by non-invasive brain stimulation and substance use and addiction are encouraged to apply.

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