Simpler Grants.gov #RFA-NS-25-017

NIH Solicitation for Advanced Neural Recording and Modulation Technologies

This opportunity from the National Institutes of Health (NIH) invites proposals to advance instrumentation and device technologies for neural recording and modulation as part of the BRAIN Initiative. - Government Buyer: - National Institutes of Health (NIH) - Scope of Work: - Development and optimization of hardware, devices, and associated software for recording and manipulating neural activity - Technologies may use optical, electrical, magnetic, or acoustic modalities - Solutions must be validated in vivo in behaving animals - Excludes projects focused primarily on molecular reagent development - Eligibility and Participation: - Open to businesses, government entities, nonprofits, and educational institutions - No specific OEMs or vendors are named; opportunity is open to all qualified applicants - Notable Requirements: - Technologies should reduce barriers to neurobiological experiments and enable new discoveries in neural circuit function - Emphasis on compatibility with live animal research and demonstration of impact - No specific products, part numbers, or quantities are listed, as this is a research and development solicitation

Description

This Notice of Funding Opportunity (NOFO) seeks applications to optimize instrumentation and device technologies for recording and modulation of neural cells and circuits to address major challenges and enable transformative understanding of dynamic signaling in the central nervous system. Proposed technologies should have demonstrated transformative potential through initial proof-of-concept testing and be ready for accelerated refinement through iterative engineering and end-user feedback. Applications may propose development of instrumentation hardware and/or devices and associated software using modalities such as optical, electrical, magnetic, or acoustic recording/manipulation. The technologies should reduce barriers to neurobiological experiments, be compatible with in vivo validation in behaving animals, and contribute to an ecosystem of technologies spanning multiple spatial and temporal scales in the CNS.

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