Simpler Grants.gov #PAR-25-060

NIH IGNITE Grant for Model Systems in Neurotherapeutic Discovery

This opportunity from the National Institutes of Health (NIH) seeks applications for the IGNITE program to advance neurotherapeutic discovery through improved model systems. - Government Buyer: - National Institutes of Health (NIH) - Products/Services Requested: - Research services for the development and validation of animal models and ex vivo systems that accurately replicate neurological or neuromuscular disorders - Focus on models with high translational relevance for efficacy assessments in both preclinical and clinical research - OEMs and Vendors: - No specific OEMs or vendors are named, as this is a research grant - Unique or Notable Requirements: - Open to a broad range of applicants: government, nonprofits, educational institutions, and businesses - Clinical trials are not permitted under this funding opportunity - Emphasis on innovative model systems that facilitate neurotherapeutic development - No cost sharing or matching required - Estimated Grant Value: - $750,000 - Place of Performance: - National Institutes of Health (NIH)

Description

This funding opportunity encourages the development and validation of animal models and human/animal tissue ex vivo systems that replicate characteristics of neurological or neuromuscular disorders. The goal is to improve the translational relevance of these models to facilitate neurotherapeutic development. Proposed models should enable meaningful efficacy assessments applicable in both preclinical and clinical settings. This FOA is part of the IGNITE Program focused on early drug discovery stages.

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