Simpler Grants.gov #PAR-25-206

NIH Pilot Effectiveness Trials for Post-Acute Mental Health Interventions (R01 Clinical Trial Required)

This opportunity from the National Institutes of Health (NIH), specifically the National Institute of Mental Health (NIMH), invites applications for pilot effectiveness research on post-acute mental health interventions. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Mental Health (NIMH) - Scope: - Soliciting pilot research projects to evaluate therapeutic and service delivery interventions for post-acute management of mental health conditions - Focus on interventions that consolidate treatment gains, manage residual symptoms, prevent relapse, and promote adherence - Requirements: - Projects must assess feasibility, tolerability, acceptability, safety, and preliminary effectiveness - Engagement of target mechanisms should be evaluated - Results intended to inform larger-scale effectiveness trials - Eligibility: - Open to government, nonprofit, educational, and business entities, including minority-serving institutions and federal agencies - No specific OEMs, vendors, products, or part numbers are referenced, as this is a grant for research services, not a procurement of goods

Description

The National Institute of Mental Health (NIMH) seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for post-acute management of mental health conditions. These interventions should be matched to the stage of illness and focus on consolidating treatment gains, managing residual symptoms, preventing relapse, and promoting adherence. The pilot trials aim to assess feasibility, tolerability, acceptability, safety, and potential effectiveness, as well as engagement of target mechanisms. This funding opportunity supports pilot research to inform the design of larger-scale effectiveness trials.

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