Simpler Grants.gov #RFA-DK-26-303

NIH Kidney Precision Medicine Project Central Hub Support Services

This opportunity from the National Institutes of Health (NIH) seeks a Central Hub (CH) for the Kidney Precision Medicine Project (KPMP): - The CH will: - Collect and de-identify clinical data and biospecimens from participants with acute kidney injury or chronic kidney disease - Provide scientific, infrastructure, quality control, project management, and administrative support for the KPMP cohort - Collaborate with Recruitment Sites, Tissue Interrogation Sites, and the Kidney Tissue Atlas Coordinating Center - Analyze kidney biopsies to create a Kidney Tissue Atlas, define disease subgroups, and identify critical cells, pathways, and therapeutic targets - No specific OEMs, vendors, or commercial products are named or required - The opportunity is a cooperative agreement with an estimated total funding of $5,000,000 - Eligible applicants include government entities, educational institutions, businesses, nonprofits, and foreign organizations - Unique requirements: - Emphasis on scientific collaboration and data/sample management - Focus on supporting a national research cohort and developing a comprehensive kidney tissue atlas

Description

This Notice of Funding Opportunity (NOFO) requests applications for the Kidney Precision Medicine Project (KPMP) - Central Hub (CH) to support the KPMP cohort, collect and de-identify all existing and new clinical data and samples, and provide scientific, infrastructure, quality control, project management, and administrative support. The CH will collaborate with the Recruitment Sites (RS), Tissue Interrogation Sites (TIS), and Kidney Tissue Atlas Coordinating Center (KTACC) to obtain and evaluate kidney biopsies from participants with acute kidney injury (AKI) or chronic kidney disease (CKD), create a Kidney Tissue Atlas, define disease subgroups, and identify critical cells, interstitial components, pathways, and targets for novel therapies.

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