Simpler Grants.gov #RFA-AG-26-023

Presolicitation for Integrative Genomic Research on Alzheimer's Disease by NIH/NIA

The National Institute on Aging (NIA), part of the National Institutes of Health (NIH), is preparing to announce a funding opportunity for integrative genomic research on Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD). - Government Buyer: - National Institute on Aging (NIA), National Institutes of Health (NIH) - Research Focus: - Projects investigating the genomic basis of AD/ADRD - Emphasis on cross-disciplinary and integrative approaches - Technologies and Methods: - Advanced analytical methods such as machine learning, comparative genomic analysis, and genome editing - Functional characterization assays, single-cell and spatial omics technologies - Use of sophisticated disease models, including human stem cell-based systems, ex vivo and in vivo models, and various model organisms - Goals: - Identify actionable therapeutic targets for AD/ADRD - Advance understanding of neurodegeneration and neuropathogenesis - Notable Requirements: - No specific OEMs, vendors, or products are named - This is a presolicitation notice; applications are not yet being accepted - Notice is intended to encourage collaboration and project development in advance of the formal solicitation

Description

The National Institute on Aging (NIA) plans to publish a Notice of Funding Opportunity (NOFO) to support integrative, cross-disciplinary projects aimed at understanding the genomic basis of Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD). Research projects will use interdisciplinary approaches, including machine learning, genome editing, and advanced disease models, to investigate genomic drivers of neurodegeneration. The goal is to identify actionable therapeutic targets for AD/ADRD. Applications are not currently being solicited; this notice is to allow potential applicants to develop collaborations and responsive projects.

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