Simpler Grants.gov #FOR-HG-26-003

NIH Forecast: Ancient DNA for Modern Genomics (aDMG) Data Generation and Resource Center

The National Institutes of Health (NIH), through the National Human Genome Research Institute (NHGRI), is forecasting a funding opportunity to establish an ancient DNA for Modern Genomics (aDMG) Data Generation and Resource Center. - Government Buyer: - National Institutes of Health (NIH) - National Human Genome Research Institute (NHGRI) - Purpose and Scope: - Establish a center to generate, harmonize, and centralize high-quality whole-genome sequence data from ancient and historical human DNA (aDNA) sources - Create an ethical, accessible resource for the scientific community - Integrate new data with existing datasets into a centralized data portal - Products/Services Requested: - Generation of whole-genome sequence data from ancient human DNA - Data harmonization and computational genomics services - Development and maintenance of a centralized data portal - Notable Requirements: - Emphasis on ethical sourcing and use of ancient DNA - Collaboration across DNA sequencing, computational genomics, data science, and human evolution disciplines - No specific OEMs, vendors, or part numbers identified in the notice - Funding and Eligibility: - Expected program funding: $2,750,000 - Cooperative agreement instrument - Open to government, business, nonprofit, and educational institutions - No cost sharing or matching required

Description

The National Human Genome Research Institute (NHGRI) intends to establish an ancient DNA for Modern Genomics (aDMG) program to create an ethical resource of ancient and historical human DNA data. The Data Generation and Resource Center will produce high-quality whole-genome sequence data from approved ancient DNA sources and harmonize it with existing data to create a centralized data portal. This program aims to advance studies about contemporary human traits and biology. Applications are not currently being solicited; this notice allows potential applicants time to develop collaborations and projects. The NOFO will use the U24 activity code and encourages collaborative investigations combining expertise in DNA sequencing, computational genomics, human evolution, and ancient human populations.

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