Simpler Grants.gov #PAR-25-052

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention

This opportunity from the National Institutes of Health (NIH) seeks applications for clinical trials and biomarker studies related to stroke treatment, recovery, and prevention, to be conducted within the NIH StrokeNet infrastructure. - Government Buyer: - National Institutes of Health (NIH) - NIH StrokeNet infrastructure includes: - National Coordinating Center (NCC) - National Data Management Center (NDMC) - Regional Coordinating Centers (RCCs) with affiliated clinical sites - Products/Services Requested: - Implementation of multi-site exploratory and confirmatory clinical trials - Biomarker or outcome measure validation studies - Ancillary studies related to stroke - Collaboration with NIH StrokeNet centers for study execution, recruitment, retention, and data management - OEMs and Vendors: - No specific OEMs or vendors are mentioned; this is a research grant opportunity, not a product procurement - Unique or Notable Requirements: - Applicants must collaborate with NIH StrokeNet infrastructure - Support provided by coordinating centers for study implementation and data management - Wide eligibility: government entities, educational institutions, nonprofits, and businesses - Funding instrument is a cooperative agreement (UG3/UH3 Clinical Trial Optional)

Description

This Notice of Funding Opportunity (NOFO) encourages applications for multi-site exploratory and confirmatory clinical trials focused on promising interventions; biomarker or outcome measure validation studies preparatory to trials in stroke prevention, treatment, and recovery; and ancillary studies to add scientific aims to active studies within StrokeNet. Successful applicants will collaborate and conduct studies within the NIH StrokeNet infrastructure, with support from the National Coordinating Center, National Data Management Center, and Regional Coordinating Centers. The goal is to efficiently implement proposed studies with recruitment, retention, and on-site clinical protocol support.

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