Opportunity
Simpler Grants.gov #FOR-CA-25-090
NCI Forecasts Funding for Pharmacokinetics Resource Laboratory to Support ETCTN Clinical Trials
Buyer
National Institutes of Health
Posted
June 27, 2025
Respond By
October 30, 2025
Identifier
FOR-CA-25-090
NAICS
541715
The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), is planning to release a funding opportunity for a Pharmacokinetics Resource Laboratory (PK Laboratory) to support the Experimental Therapeutics Clinical Trials Network (ETCTN): - The PK Laboratory will: - Organize biospecimen collections for ETCTN clinical trials - Conduct analyses of pharmacokinetic endpoints, drug-drug interactions, cytochrome P450 interactions, pharmacodynamics, and food effects for NCI Investigational New Drug (IND) agents - Provide technical services, scientific leadership, and biospecimen management - The opportunity is open to multidisciplinary institutions or organizations with established infrastructure for PK studies - No specific OEMs or commercial vendors are named, as this is a research and service-focused opportunity - Anticipated funding is $850,000, with one award expected - Eligible applicants include nonprofits and higher education institutions - Unique requirements: - Applicants must demonstrate capacity for comprehensive PK analyses and biospecimen management - Multidisciplinary expertise and infrastructure are required
Description
The National Cancer Institute (NCI) plans to publish a Notice of Funding Opportunity (NOFO) to solicit applications from institutions to maintain or establish a Pharmacokinetics Resource Laboratory (PK Laboratory) supporting the Experimental Therapeutics Clinical Trials Network (ETCTN). The PK Laboratory will manage biospecimen collections and analyze pharmacokinetic endpoints, drug interactions, pharmacodynamics, and food effects in ETCTN studies of NCI Investigational New Drug agents. The goal is to advance clinical development of these agents by providing comprehensive pharmacokinetic data. Applications will include cores for technical services, scientific leadership, and biospecimen management. The NOFO is expected to be published in Summer 2025 with applications due in Fall 2025.