Opportunity
Simpler Grants.gov #PAR-25-154
NIH HEAL Initiative Funding for Early-Stage Discovery of New Pain Targets in the Druggable Proteome
Buyer
National Institutes of Health
Posted
December 11, 2024
Respond By
July 16, 2026
Identifier
PAR-25-154
NAICS
541715
This opportunity from the National Institutes of Health (NIH) seeks pilot research projects under the HEAL Initiative to identify new druggable targets for pain within the understudied druggable proteome. - Government Buyer: - National Institutes of Health (NIH) - Multiple sub-agencies involved, including Alcohol Research Programs, Child Health and Human Development, Aging Research, Neurosciences, Drug Use and Addiction, Arthritis and Musculoskeletal Diseases, Oral Diseases, National Center for Advancing Translational Sciences, and Complementary and Integrative Health - Products/Services Requested: - Research services for discovery of new pain targets - Generation of preliminary data and research tools - Basic biochemical and biological characterization of understudied proteins - OEMs and Vendors: - No specific OEMs or vendors are named, as this is a research grant - Unique/Notable Requirements: - Focus on basic research (not clinical trials) - Eligible applicants include nonprofits, government, businesses, educational institutions, and certain tribal/minority-serving institutions - Minimum award is $100,000 - No cost sharing or matching required - Emphasis on accelerating pain management and opioid addiction solutions
Description
This notice of funding opportunity (NOFO) solicits applications for pilot projects to identify new druggable targets for pain within the understudied druggable proteome. Awards will support generation of preliminary data and/or tools around eligible understudied proteins to jumpstart research on these proteins in the context of pain and pain management. The funding aims to support basic biochemical and biological work to characterize understudied proteins to identify new druggable targets for pain. This initiative is part of the NIH Helping to End Addiction Long Term (HEAL) initiative to accelerate development of novel medications for opioid addiction.