Simpler Grants.gov #PAR-25-281

NIH Grant for Translational Research on Mood and Psychosis During Menopause Transition

The National Institutes of Health (NIH) is seeking proposals for translational research focused on mood and psychosis symptoms during the menopause transition. - Government Buyer: - National Institutes of Health (NIH) - Scope of Research: - Translational research to understand the emergence and worsening of mood and psychotic disorders during menopause transition - Disorders of interest include perimenopausal depression, generalized anxiety disorder, bipolar disorder, and schizophrenia - Emphasis on neurobiological and behavioral mechanisms, including the role of reproductive steroids, menopausal stage diagnosis, co-occurring psychiatric and menopause symptoms, psychosocial factors, and differential diagnoses - Requirements: - Interdisciplinary collaboration is encouraged - Hypothesis-driven studies to identify targets for future novel treatment interventions - No specific products, OEMs, or vendors are required, as this is a grant for research activities - Funding Mechanism: - Issued under Assistance Listings 93.242 (Mental Health Research Grants) and 93.313 (NIH Office of Research on Women's Health)

Description

This Notice of Funding Opportunity (NOFO) aims to advance translational research to better understand the emergence and worsening of mood and psychotic disorders during the menopause transition. The research focuses on neurobiological and behavioral mechanisms underlying mood and psychosis symptoms, including depressive symptoms combined with menopause symptoms, reproductive steroid roles, diagnosis at menopausal stage, co-occurring psychiatric and menopause symptoms, psychosocial factors, and differential diagnoses. Interdisciplinary collaboration is encouraged to identify targets for novel treatment interventions. The funding supports hypothesis-driven work with a focus on comprehensive neurobiology and mechanisms of action.

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