Simpler Grants.gov #PAR-25-177

NIH Solicitation for Clinical Trials on Mental Health Interventions (R01 - Clinical Trial Required)

This opportunity from the National Institutes of Health (NIH) seeks applications for clinical trials focused on mental health interventions. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Mental Health (NIMH) - OEMs and Vendors: - No specific OEMs or vendors are mentioned, as this is a research grant opportunity, not a product procurement. - Products/Services Requested: - Conduct full-scale hybrid effectiveness-implementation clinical trials - Focus on therapeutic, preventive, and services interventions for mental health - Trials should be conducted in community and practice settings - Services interventions may target patient, provider, organizational, or systems levels - No specific part numbers or product quantities are requested - Unique or Notable Requirements: - Applicants must address significant mental health problems - Proposals should include well-justified hypotheses supported by pilot data - Studies must examine mediators and moderators of intervention effects - Open to a wide range of organizations, including educational, nonprofit, business, government, tribal, and certain foreign entities - No product purchases are involved; this is for research activities only

Description

This funding opportunity supports clinical trials to test the effectiveness of treatment, preventive, and services interventions for mental health. It aims to support trials that address significant problems with potential to inform practice, are adequately powered to answer primary research questions, and examine mediators and moderators of effects. The trials focus on optimized therapeutic and preventive interventions in community and practice settings, as well as services interventions to improve access, quality, equity, and value of mental health services.

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