Opportunity

Simpler Grants.gov #FOR-HG-26-005

Presolicitation: Clinical Data Ecosystem for Genomics (CDEG) Research Network

Buyer

National Institutes of Health

Posted

July 17, 2025

Respond By

March 02, 2026

Identifier

FOR-HG-26-005

NAICS

541715, 541511

The National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) is preparing to release a Notice of Funding Opportunity (NOFO) for research to advance a Clinical Data Ecosystem for Genomics (CDEG). - Government Buyer: - National Institutes of Health (NIH) - National Human Genome Research Institute (NHGRI) - Purpose and Scope: - Establish a research network to improve clinical integration and sharing of genome sequencing data as structured data - Facilitate data exchange among laboratories, healthcare providers, and patients - Develop a pilot ecosystem, standardized APIs, open-source clinical software applications, and databases - Demonstrate the ability to share genomic data across healthcare systems - Products/Services Requested: - Research and development services for clinical data integration - Creation of open-source software and standardized APIs - No specific part numbers, OEMs, or vendors are named - Unique Requirements: - Focus on interoperability, open-source solutions, and standardized data sharing - Intended for organizations with expertise in genomic medicine, computational genomics, data science, EHR integration, genomic data standards, cloud/database development, health information exchange, and clinical genomics implementation - No applications are being accepted yet; this is a forecasted opportunity

Description

The National Human Genome Research Institute (NHGRI) plans to publish a Notice of Funding Opportunity (NOFO) to solicit research applications aimed at reducing barriers to a Clinical Data Ecosystem for Genomics (CDEG). The project involves establishing a network to identify, share, and improve approaches for clinical integration and sharing of genome sequencing data as structured data among labs, healthcare providers, and patients. The network will establish a pilot ecosystem demonstrating best practices, create standardized APIs, develop open-source clinical software, and demonstrate the ecosystem's ability to overcome barriers to accessing patient genomic data across healthcare systems. Applications are not currently being solicited; this notice allows potential applicants to prepare collaborations and projects.

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