Simpler Grants.gov #PAR-25-227

NIH Grant for Research on Disorders Detectable by Newborn Screening

This opportunity from the National Institutes of Health (NIH) seeks research grant applications focused on disorders detectable through newborn screening. - Government Buyer: - National Institutes of Health (NIH) - Child Health and Human Development Extramural Research (Assistance Listing 93.865) - OEMs and Vendors: - No specific OEMs or vendors are named, as this is a research grant rather than a product or service procurement - Products/Services Requested: - Research activities to expand knowledge of the natural history of disorders included in or potentially included in statewide newborn screening programs - Characterization of symptom development - Establishment of genotype-phenotype correlations - Identification of genetic, epigenetic, or environmental modifiers - Creation of data collection systems or patient registries for longitudinal data - Unique or Notable Requirements: - Supports a wide range of eligible applicants, including educational institutions, nonprofits, government entities, and businesses - Focus on facilitating appropriate interventions for infants identified by newborn screening - No specific products, part numbers, or purchase quantities are specified, as this is a research funding opportunity

Description

This Notice of Funding Opportunity (NOFO) encourages applications to expand knowledge of the natural history of disorders that are or may become part of statewide newborn screening programs. The goal is to facilitate appropriate interventions for infants identified by newborn screening by understanding the sequence and timing of symptom development. The research aims to identify biological mechanisms, improve diagnostic accuracy, facilitate clinical trials, and support families with predictive information. Establishing genotype-phenotype correlations and identifying modifying factors are also key objectives.

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