Simpler Grants.gov #PAR-25-024

NIH Grant for Biomarker Discovery and Early Evaluation in Neurological Disorders

This opportunity from the National Institutes of Health (NIH) supports research on biomarker discovery and early evaluation for neurological and neuromuscular disorders. - Government Buyer: - National Institutes of Health (NIH) - Extramural Research Programs in the Neurosciences and Neurological Disorders (Assistance Listing 93.853) - Aging Research (Assistance Listing 93.866) - Products/Services Requested: - Research services for the identification, biological, analytical, and clinical evaluation of candidate biomarkers and biomarker signatures - Includes preliminary human evaluation using standardized samples or datasets - Projects must deliver candidate biomarkers or signatures ready for definitive validation studies - Unique/Notable Requirements: - Mandatory preliminary human evaluation - Option to include clinical trials - Open to a wide range of applicants: government, nonprofits, educational institutions, small businesses, and others - No specific OEMs or vendors are named, as this is a research grant, not a product procurement - Place of Performance/Contracting Office: - National Institutes of Health (federal office)

Description

This Funding Opportunity Announcement (FOA) aims to promote the discovery and early evaluation of candidate biomarkers and biomarker signatures to facilitate clinical development of neurotherapeutics and their clinical use. The focus is on identifying and initially evaluating biomarkers for neurological and neuromuscular disorders, including preliminary human evaluation with standardized samples or datasets. The goal is to deliver candidate biomarkers ready for definitive analytical and clinical validation studies. Research may include animal studies but must involve human evaluation.

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