Simpler Grants.gov #TEMP-31126

NIH Funding for Research on Environmental Exposures and Gut-Brain Signaling in Neurological Diseases

This opportunity from the National Institutes of Health (NIH), led by the National Institute of Environmental Health Sciences (NIEHS), seeks research proposals on environmental exposures and their effects on gut-brain signaling in neurological conditions. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Environmental Health Sciences (NIEHS) - Focus Areas: - Research on the impact of environmental exposures on the gut microbiome-brain axis - Targeting neurological diseases, including mental health disorders, Parkinson’s, and Alzheimer’s disease - Products/Services Requested: - Development of gut-focused interventions such as: - Probiotics - Microbial biomarkers - Nutritional supplements - Novel therapeutics - No specific part numbers or quantities; this is a research grant - Unique Requirements: - Encourages collaborative, multidisciplinary research (toxicology, microbiome, neuroscience) - Supports development of detection, prevention, and intervention strategies - Foreign components allowed per NIH policy - Utilizes the R01 grant mechanism - Estimated Funding: - $4,000,000 total, with approximately 8 awards anticipated - No OEMs or commercial vendors specified, as this is a research funding opportunity

Description

The National Institute of Environmental Health Sciences (NIEHS) intends to solicit research applications to enhance understanding of the gut microbiome-brain axis to improve detection, prevention, and intervention strategies for neurological diseases caused by environmental exposures. The program covers a broad range of neurological outcomes including mental health disorders and chronic neurodegenerative diseases such as Parkinson's and Alzheimer's. The goal is to develop gut-focused interventions like probiotics, microbial biomarkers, nutritional supplements, and novel therapeutics to reduce risk, slow progression, or reverse neurological conditions. Collaborative research combining toxicology, microbiome, and neuroscience expertise is encouraged. Applications are not currently being solicited; this notice allows potential applicants time to prepare.

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