Opportunity
Simpler Grants.gov #FOR-RFA-AG-26-019
Funding Opportunity for Multi-Site Alzheimer's Disease Clinical Trials Using ACTC Infrastructure
Buyer
National Institutes of Health
Posted
June 27, 2025
Respond By
October 05, 2025
Identifier
FOR-RFA-AG-26-019
NAICS
541715
This opportunity from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), seeks applications for multi-site clinical trials targeting Alzheimer's disease and related dementias. - Government Buyer: - National Institutes of Health (NIH), National Institute on Aging (NIA) - OEMs and Vendors: - No specific OEMs or vendors are mentioned; this is a grant for clinical research, not a product procurement - Products/Services Requested: - Funding for Phase Ib to III clinical trials using the Alzheimer's disease Clinical Trials Consortium (ACTC) infrastructure - Interventions may be pharmacological or non-pharmacological, aimed at prevention, delay, or treatment of Alzheimer's disease and related dementias - No part numbers or product quantities specified - Unique or Notable Requirements: - Mandatory use of ACTC infrastructure for trial execution - Collaboration required between applicants, NIA, and ACTC leadership - Open to a wide range of organizations, including small businesses, nonprofits, educational institutions, and government entities - Focus on cognitive and neuropsychiatric outcomes across all disease stages
Description
The National Institute on Aging (NIA) plans to publish a Notice of Funding Opportunity (NOFO) to invite applications for multi-site Phase Ib to III clinical trials of pharmacological and non-pharmacological interventions aimed at preventing, delaying, or treating Alzheimer's disease and related dementias. The trials will utilize the Alzheimer's disease Clinical Trials Consortium (ACTC) infrastructure, with collaboration between applicants, NIA, and ACTC leadership. This initiative targets cognitive and neuropsychiatric changes associated with age-related cognitive decline and Alzheimer's disease across various stages. Applications are not currently being solicited; this notice allows potential applicants time to prepare collaborations and projects.