Simpler Grants.gov #FOR-TR-27-002

NIH Solicits Research Proposals for Extracellular Vesicle Therapeutics in Regenerative Medicine

The National Institutes of Health (NIH), through the National Center for Advancing Translational Sciences (NCATS), is inviting research proposals for the Extracellular Vesicle Therapeutics for Regenerative Medicine (ExTReMe) program. - Government Buyer: - National Institutes of Health (NIH) - National Center for Advancing Translational Sciences (NCATS) - Products/Services Requested: - Research and development services focused on extracellular vesicle (EV)-based therapeutics for regenerative medicine - Includes both direct EV therapies produced under GLP conditions and designer EVs tailored to individual patient needs - Eligible Applicants: - Nonprofits, educational institutions, government entities, and businesses - Unique/Notable Requirements: - Emphasis on cell-free EVs as therapeutic tools - Focus on engineering EVs for delivery of therapeutic agents or modulation of tissue repair pathways - No cost sharing or matching required - Funding instrument is a cooperative agreement - No specific OEMs, vendors, or commercial products are named, as this is a research grant opportunity - Place of performance is the National Center for Advancing Translational Sciences (NCATS)

Description

The National Center for Advancing Translational Science (NCATS) seeks to advance research on extracellular vesicles (EVs) and their use as therapeutics in regenerative medicine. The program aims to support the translation of EV-based therapeutics, including direct EV therapy and designer EVs personalized to patient needs. EVs are natural mediators of intercellular communication and can be engineered to deliver therapeutic agents or modulate repair pathways. This opportunity is funded through a cooperative agreement and targets various eligible applicants including nonprofits, educational institutions, governments, and businesses.

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