Simpler Grants.gov #FOR-AR-26-010

NIH Seeks Research on Skin Injury Mechanisms from Toxic Chemical Threats

The National Institutes of Health (NIH), through its National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Institute of Allergy and Infectious Diseases (NIAID), is seeking research proposals focused on chemical threats to skin health. - Government Buyer: - National Institutes of Health (NIH) - Sub-agencies: NIAMS and NIAID - Scope of Research: - Investigate pathological mechanisms of skin injury caused by toxic chemicals identified as high-consequence public health threats by the Department of Homeland Security - Target chemicals include: - Vesicants: sulfur mustard, Lewisite, nitrogen mustard, phosgene oxime - Arsenicals and other toxic agents - Applicants must study at least two chemicals from different toxidromes - Research should focus on molecular and cellular pathology, identification of shared therapeutic targets, and development of broad-spectrum medical countermeasures for mass casualty events - Funding Details: - Estimated total funding: $2,500,000 - Five awards expected - Notable Requirements: - No specific OEMs, vendors, or commercial products are named; this is a research grant opportunity - Emphasis on broad-spectrum solutions and cross-toxidrome applicability - Place of Performance: - National Institutes of Health (federal office)

Description

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the National Institute of Allergy and Infectious Diseases (NIAID) are soliciting applications to study the pathological mechanisms of skin injury caused by toxic chemicals identified as high-consequence public health threats. The research will focus on understanding common mechanisms of skin injuries caused by vesicants such as sulfur mustard, Lewisite, nitrogen mustard, phosgene oxime, arsenicals, and other toxic chemicals. Applications should investigate molecular and cellular pathology of at least two chemicals from different toxidromes. The goal is to discover shared therapeutic targets and develop broad-spectrum medical countermeasures for mass casualty events involving toxic chemical exposure.

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