Award
NIH Reporter #1K99NS150641-01
Macrophage remodeling of brain extracellular matrix in Krabbe disease
Recipient
University of Pennsylvania
Award Amount
$128,925.00
Ceiling
$128,925.00
Awarded
August 07, 2026
Identifier
1K99NS150641-01
A K99/R00 research award to study how macrophages and microglia reshape brain extracellular matrix and tissue mechanics in Krabbe disease.
Description
NIH research project examining how macrophages remodel brain extracellular matrix and alter tissue mechanics in Krabbe disease, a genetic pediatric leukodystrophy. The project investigates microglial fibronectin and aims to identify mechanisms that could support recovery.