Award
NIH Reporter #5R01ES036931-02
Understanding the Origins of the Mutational Landscape in Cancer
Recipient
University of Arkansas for Medical Sciences
Award Amount
$719,050.00
Ceiling
$719,050.00
Awarded
January 13, 2026
Identifier
5R01ES036931-02
The University of Arkansas for Medical Sciences received NIH funding to study the origins of cancer-associated mutations, including the contributions of environmental exposures and endogenous processes.
Description
Research project investigating how environmental mutagens and endogenous processes contribute to DNA lesions and mutational signatures in cancer. The project studies 1,2,3-Trichloropropane, bromochloroacetic acid, and furan using DNA adductomics, Nanopore sequencing, and duplex sequencing.