Award
NIH Reporter #1RC2DK144820-01A1
Interorgan Genomic Atlas for Discovery of Bioenergetic Dynamics and Mechanisms of Time-Restricted Feeding
Recipient
Northwestern University
Award Amount
$1,641,136.00
Ceiling
$1,641,136.00
Awarded
September 17, 2026
Identifier
1RC2DK144820-01A1
NIH-funded research at Northwestern University studying how feeding schedules affect metabolism and bioenergetic processes across organs, with genomic analyses and a public knowledge portal.
Description
The project examines how feeding time influences energy balance and nutrient processing across multiple organs. Researchers will perform bulk and single-nuclei genomic analyses across the light-dark cycle in liver, adipose tissue, and intestine of mice under different feeding schedules and diets at thermoneutrality. The project also includes development of a publicly accessible Time-Restricted Feeding Knowledge Portal integrated with the Common Metabolic Disease Knowledge Portal.