Award
NIH Reporter #4DP2CA290244-02
Simulating Ancestrally Unbiased Tumor Evolution To Interrogate Drug Resistance
Recipient
University of California, San Francisco
Award Amount
$984,000.00
Ceiling
$984,000.00
Awarded
September 17, 2026
Identifier
4DP2CA290244-02
The award supports research into how tumor ancestry and anatomic niches influence tumor evolution and drug resistance, using an organoid-based model to identify and test potential therapeutic targets.
Description
Research project developing BRUTE, an immunocompetent organoid-based tumor graft system, to study ancestry-associated tumor evolution, drug resistance, and potential therapeutic targets.